Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20070372 | 0.87 | SIGMAR1 (0.56) | SIGMAR1CYP2D6USP2POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL20138396 | 0.85 | SIGMAR1 (0.55) | SIGMAR1CYP2D6USP2SLC6A4ALDH1A1 | |
| SCHEMBL25596166 | 0.73 | SIGMAR1 (0.41) | SIGMAR1CYP2D6USP2CYP1A2SLC6A4 | |
| SCHEMBL27932886 | 0.73 | GAA (0.51) | SIGMAR1CYP2D6USP2CYP1A2CHRM2 | |
| SCHEMBL16657601 | 0.73 | FPR2 (0.53) | SIGMAR1CYP2D6USP2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL28086905 | 0.72 | FPR2 (0.52) | SIGMAR1CYP2D6USP2SLC6A4APOBEC3A | |
| SCHEMBL7290612 | 0.72 | LMNA (0.46) | SIGMAR1SLC6A4MEN1KMT2A | |
| SCHEMBL7446267 | 0.71 | POLB (0.56) | POLBBRD4KDM4EALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL20137513 | 0.71 | LMNA (0.49) | SIGMAR1SLC6A4MEN1KMT2A | |
| SCHEMBL8401996 | 0.71 | CYP1A2 (0.76) | CYP2D6USP2POLBCYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768958-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2005121088-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |