Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522609 | 0.85 | LMNA (0.37) | OPRM1SPHK1LMNA | |
| SCHEMBL5807043 | 0.84 | ACE2 (0.37) | ACE2OPRM1SPHK1LMNAPTPN1 | |
| SCHEMBL1133423 | 0.83 | LMNA (0.38) | OPRM1SPHK1LMNA | |
| SCHEMBL27520359 | 0.83 | LMNA (0.38) | OPRM1SPHK1LMNA | |
| SCHEMBL29010410 | 0.82 | NR1I2 (0.39) | OPRM1SPHK1LMNA | |
| SCHEMBL28030710 | 0.76 | OPRM1 (0.38) | ACE2OPRM1SPHK1LMNAADH1B | |
| SCHEMBL4275509 | 0.72 | ACE2 (0.52) | ACE2OPRM1SPHK1LMNAADH1B | |
| SCHEMBL4275317 | 0.72 | ACE2 (0.52) | ACE2OPRM1SPHK1LMNAADH1B | |
| SCHEMBL4281824 | 0.72 | ACE2 (0.52) | ACE2OPRM1SPHK1LMNAADH1B | |
| SCHEMBL4272056 | 0.72 | ACE2 (0.52) | ACE2OPRM1SPHK1LMNAADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747451-A2 | POINT OF CARE HEPARIN DETERMINATION SYSTEM | Medtronic, Inc. (US) | 2007-01-31 | — | — | EP | claimed |
| WO-2005116623-A2 | POINT OF CARE HEPARIN DETERMINATION SYSTEM | MEDTRONIC, INC. (US) | 2005-12-08 | — | — | WO | claimed |