Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133423 | 1.00 | LMNA (0.38) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL27522609 | 0.98 | LMNA (0.37) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL29010410 | 0.90 | NR1I2 (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL5498219 | 0.83 | ACE2 (0.36) | LMNAOPRM1SPHK1 | |
| SCHEMBL4441750 | 0.81 | LMNA (0.52) | LMNATSHRSPHK1MAPT | |
| SCHEMBL1702149 | 0.79 | NR1I2 (0.40) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL28030710 | 0.78 | OPRM1 (0.38) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL1018909 | 0.74 | GPR84 (0.45) | LMNAGPR84FDPSSPHK1FFAR1 | |
| Heptane SCHEMBL28061144 | 0.67 | TSHR (0.47) | LMNADNM1TSHRTHRB | |
| Cyclooctane SCHEMBL8435685 | 0.64 | TSHR (0.73) | LMNADNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225631-A | Bioconjugates of manganese or iron complexes of nitrogen-contg. macrocyclic ligands effective as catalysis for dismutating superoxide | MONSANTO CO (US) | 1999-08-11 | — | — | CN | disclosed |