Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499318 | 0.92 | KCNH2 (0.33) | DRD2CHRM1CHRM3RENKCNH2 | |
| SCHEMBL5502511 | 0.85 | TAAR1 (0.45) | DRD2RENKCNH2SLC6A2SLC6A4 | |
| SCHEMBL5495876 | 0.85 | FFAR4 (0.38) | CHRM1CHRM3RENHTR2CHTR2A | |
| SCHEMBL27618109 | 0.85 | TAAR1 (0.43) | HTR2CHTR2ASLC6A2SLC6A4HTR2B | |
| Hydrochloric Acid SCHEMBL1475155 | 0.84 | TAAR1 (0.42) | HTR2CHTR2ASLC6A2SLC6A4HTR2B | |
| SCHEMBL5501439 | 0.83 | FFAR4 (0.40) | DRD2CHRM1RENKCNH2HTR2C | |
| SCHEMBL5499300 | 0.82 | SLC6A2 (0.45) | RENKCNH2SLC6A2SLC6A4P2RX7 | |
| SCHEMBL5493839 | 0.79 | P2RX7 (0.39) | KCNH2HTR2CHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5501435 | 0.79 | KCNH2 (0.38) | DRD2RENKCNH2SLC6A2SLC6A4 | |
| SCHEMBL5500299 | 0.77 | TAAR1 (0.42) | DRD2RENKCNH2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005121092-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |