Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724862 | 1.00 | DRD2 (0.61) | DRD2DRD3HTR1APOLBTSHR | |
| SCHEMBL9527919 | 0.92 | HTR1A (0.62) | DRD2DRD3HTR1APOLBTSHR | |
| SCHEMBL8957751 | 0.90 | DRD2 (0.58) | DRD2DRD3HTR1APOLBHTR6 | |
| SCHEMBL7671076 | 0.82 | DRD2 (0.63) | DRD2DRD3HTR1APOLBGAA | |
| SCHEMBL13648743 | 0.81 | POLB (0.65) | DRD2DRD3HTR1APOLBHTR6 | |
| SCHEMBL6930570 | 0.79 | POLB (0.64) | DRD2DRD3HTR1APOLBHTR6 | |
| SCHEMBL11110538 | 0.79 | ALDH1A1 (0.66) | DRD2DRD3HTR1APOLBKMT2A | |
| SCHEMBL278126 | 0.79 | DRD2 (0.67) | DRD2DRD3HTR1APOLBTSHR | |
| SCHEMBL6506614 | 0.78 | DRD2 (0.58) | DRD2DRD3HTR1APOLBTSHR | |
| SCHEMBL10746398 | 0.78 | DRD2 (0.58) | DRD2DRD3HTR1APOLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778685-A1 | INDOLIZINE CARBOXAMIDES AND THE AZA AND DIAZA DERIVATIVES THEREOF | SCHWARZ PHARMA AG (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006015737-A1 | INDOLIZINE CARBOXAMIDES AND THE AZA AND DIAZA DERIVATIVES THEREOF | SCHWARZ PHARMA AG (DE) | 2006-02-16 | — | — | WO | disclosed |