Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 3/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846104 | 0.79 | HRH3 (0.36) | — | |
| SCHEMBL4105539 | 0.78 | MC4R (0.39) | IDO1MC4R | |
| SCHEMBL5489928 | 0.78 | HRH3 (0.39) | — | |
| SCHEMBL11179160 | 0.78 | HRH3 (0.39) | — | |
| SCHEMBL5499434 | 0.76 | RAB9A (0.33) | — | |
| SCHEMBL3631734 | 0.76 | GNAI3 (0.38) | SIGMAR1 | |
| SCHEMBL646006 | 0.74 | KEAP1 (0.39) | KDM4EGLASIGMAR1 | |
| SCHEMBL4508119 | 0.74 | POLB (0.38) | SIGMAR1 | |
| SCHEMBL4831887 | 0.73 | KMT2A (0.42) | IDO1KDM4EGLA | |
| SCHEMBL25700799 | 0.72 | KDM4E (0.40) | MC4RPAOXKDM4EGLASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005470-B1 | OXINDOLYLQUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | EP | disclosed |