Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 10/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 1/20 | 0.65 |
| ▸ | CCKAR | P32238 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731310 | 0.82 | HMGCR (0.59) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL9731305 | 0.82 | HMGCR (0.59) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL10396849 | 0.82 | HMGCR (0.77) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL10396848 | 0.82 | HMGCR (0.77) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL8952976 | 0.79 | HMGCR (0.69) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL8952968 | 0.79 | HMGCR (0.69) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL9729978 | 0.79 | HMGCR (0.52) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| SCHEMBL9729969 | 0.79 | HMGCR (0.52) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| Fluvastatin SCHEMBL628757 | 0.79 | HMGCR (1.00) | HMGCRCYP2C9SIRT6TBXA2RADRA1A | |
| Fluvastatin SCHEMBL13501651 | 0.79 | HMGCR (1.00) | HMGCRCYP2C9SIRT6TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054860-B1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIOLS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2007-04-25 | — | — | EP | disclosed |
| US-6962994-B2 | Process for the synthesis of 1,3-diols | WARNER-LAMBERT COMPANY, LLC (US) | 2005-11-08 | — | — | US | disclosed |
| US-20050197500-A1 | Process for the synthesis of 1,3-diols | BOSCH ROBERT L (US) | 2005-09-08 | — | — | US | disclosed |
| US-20040006231-A1 | Process for the synthesis of 1,3-diols | BOSCH ROBERT LEE (US) | 2004-01-08 | — | — | US | disclosed |
| US-6596879-B2 | Beta hydroxy ketone treated with trialkylborane or dialkylalkoxyborane followed by recovery and reuse of alkylborane | WARNER-LAMBERT COMPANY | 2003-07-22 | — | — | US | disclosed |
| US-20020161021-A1 | Process for the synthesis of 1,3-diols | BOSCH ROBERT LEE (US) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197500-A1 | Process for the synthesis of 1,3-diols | HSD17B7, HSD11B1, BCKDK | HMGCR 160/4885CYP2C9 276/4885SIRT6 4380/4885 |
| US-20020161021-A1 | Process for the synthesis of 1,3-diols | HSD17B7, HSD11B1, BCKDK | HMGCR 160/4885CYP2C9 276/4885SIRT6 4380/4885 |
| US-20040006231-A1 | Process for the synthesis of 1,3-diols | HSD17B7, HSD11B1, BCKDK | HMGCR 160/4885CYP2C9 276/4885SIRT6 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.