Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.47 |
| ▸ | FAP | Q12884 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400667 | 0.85 | HTT (0.53) | DPP4ALDH1A1SMN1; SMN2ACEHTT | |
| SCHEMBL27695426 | 0.85 | HTT (0.53) | DPP4ALDH1A1SMN1; SMN2ACEHTT | |
| SCHEMBL28715490 | 0.83 | SMN1; SMN2 (0.51) | TSHRMAPK1NPSR1PREPFAP | |
| SCHEMBL27449952 | 0.83 | PREP (0.48) | TSHRMAPK1NPSR1PREPFAP | |
| SCHEMBL2226530 | 0.77 | ALDH1A1 (0.66) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL4893223 | 0.77 | ALDH1A1 (0.66) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL6860849 | 0.75 | ALDH1A1 (0.50) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL2218785 | 0.75 | HTT (0.51) | PREPFAPDPP4ACEHTT | |
| SCHEMBL29634427 | 0.75 | HTT (0.63) | TSHRMAPK1NPSR1HDAC1HDAC6 | |
| SCHEMBL21675408 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ACEHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | THE PROCTER & GAMBLE COMPANY | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | SLC1A5, SLC19A1, PLPBP | TSHR 4281/4885MAPK1 3514/4885NPSR1 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.