Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 4/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499457 | 0.84 | AHR (0.42) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL5504321 | 0.80 | GRIA1 (0.39) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL5504031 | 0.77 | ALOX15 (0.41) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL5503888 | 0.77 | AHR (0.39) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL188979 | 0.77 | GRIA1 (0.37) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL4660496 | 0.76 | AHR (0.41) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL2491904 | 0.76 | AHR (0.50) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL5499322 | 0.76 | EPHX2 (0.39) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL5503130 | 0.75 | AR (0.40) | GRIA1CACNG8AHRCMA1EIF2AK2 | |
| SCHEMBL2486755 | 0.74 | GRIA1 (0.51) | GRIA1CACNG8AHRCMA1EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |