Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249468 | 0.78 | MAP3K14 (0.35) | GLA | |
| SCHEMBL7270134 | 0.75 | MAP3K14 (0.33) | GLA | |
| SCHEMBL15550401 | 0.75 | GLA (0.30) | GLA | |
| SCHEMBL7404277 | 0.72 | MAP3K14 (0.33) | — | |
| SCHEMBL11154702 | 0.72 | ALDH1A1 (0.43) | — | |
| SCHEMBL8891060 | 0.71 | DPP4 (0.34) | GLA | |
| SCHEMBL20292600 | 0.71 | MAP3K14 (0.36) | GLA | |
| SCHEMBL8745670 | 0.70 | MAP3K14 (0.32) | — | |
| SCHEMBL4827454 | 0.70 | MAP3K14 (0.32) | — | |
| SCHEMBL756451 | 0.70 | CRBN (0.38) | GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846405-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO 4,5-C RING COMPOUNDS AND METHODS | 3M Innovative Properties Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006086634-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-17 | — | — | WO | disclosed |