SCHEMBL5499520

CC[C@H](C)CC1(C[C@@H](C)CC)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2-c2ccc(-c3ccc4c(c3)C(C[C@@H](C)CC)(C[C@@H](C)CC)c3cc([Si](C)(C)C)ccc3-4)cc21

nearest known ligand 0.35

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	LIPG	Q9Y5X9	14/20	0.35

▸	LPL	P06858	13/20	0.35

▸	DGAT1	O75907	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6263760	0.91	LPL (0.32)	LIPGLPL
SCHEMBL19831183	0.88	LPL (0.41)	LIPGLPL
SCHEMBL5498894	0.87	LIPG (0.41)	LIPGLPLDGAT1
SCHEMBL5501737	0.87	LIPG (0.41)	LIPGLPLDGAT1
SCHEMBL5499517	0.81	LIPG (0.35)	LIPGLPLDGAT1
SCHEMBL5502525	0.80	—	—
SCHEMBL5663449	0.76	—	—
SCHEMBL5498599	0.76	PDK2 (0.32)	—
SCHEMBL3457309	0.76	LPL (0.46)	LIPGLPL
SCHEMBL5498910	0.74	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1425168-A4	LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS	UNIV ROCHESTER (US)	2007-01-03	—	—	EP	disclosed
US-7057009-B2	Crosslinking polyfluorene; molecular orientation	UNIVERSITY OF ROCHESTER (US)	2006-06-06	—	—	US	disclosed
EP-1425168-A2	LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS	University of Rochester (US)	2004-06-09	—	—	EP	disclosed
US-20030039838-A1	Light-emitting organic oligomer compositions	UNIVERSITY OF ROCHESTER	2003-02-27	—	—	US	disclosed
WO-2003008475-A2	LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS	UNIVERSITY OF ROCHESTER (US)	2003-01-30	—	—	WO	disclosed