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SCHEMBL5501737

SCHEMBL5501737

CCC(C)CC1(CC(C)CC)c2ccccc2-c2ccc(-c3ccc4c(c3)C(CC(C)CC)(CC(C)CC)c3cc(-c5ccc6c(c5)C(CC(C)CC)(CC(C)CC)c5cc(B7OC(C)(C)C(C)(C)O7)ccc5-6)ccc3-4)cc21

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LIPG Q9Y5X9 14/20 0.41
▸ LPL P06858 13/20 0.41
▸ DGAT1 O75907 1/20 0.34
▸ PRMT5 O14744 1/20 0.33
▸ WDR77 Q9BQA1 1/20 0.33
▸ BACE1 P56817 1/20 0.32
▸ ROCK1 Q13464 1/20 0.30
▸ PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5498894 1.00 LIPG (0.41) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL19831183 0.89 LPL (0.41) LIPGLPLPRMT5WDR77BACE1
SCHEMBL5499520 0.87 LIPG (0.35) LIPGLPLDGAT1
SCHEMBL431831 0.86 LIPG (0.47) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL12213298 0.83 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL12213306 0.83 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL431827 0.83 LIPG (0.44) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL14066755 0.82 LIPG (0.39) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL12056854 0.81 LIPG (0.44) LIPGLPLPRMT5WDR77BACE1
SCHEMBL29638828 0.81 LIPG (0.44) LIPGLPLPRMT5WDR77BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425168-A4 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIV ROCHESTER (US) 2007-01-03 — — EP disclosed
US-7057009-B2 Crosslinking polyfluorene; molecular orientation UNIVERSITY OF ROCHESTER (US) 2006-06-06 — — US disclosed
EP-1425168-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS University of Rochester (US) 2004-06-09 — — EP disclosed
US-20030039838-A1 Light-emitting organic oligomer compositions UNIVERSITY OF ROCHESTER 2003-02-27 — — US disclosed
WO-2003008475-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIVERSITY OF ROCHESTER (US) 2003-01-30 — — WO disclosed