Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581703 | 1.00 | SIGMAR1 (0.53) | SIGMAR1ACP3ADRA2CHSD17B10CHRM2 | |
| SCHEMBL8074825 | 1.00 | SIGMAR1 (0.53) | SIGMAR1ACP3ADRA2CHSD17B10CHRM2 | |
| SCHEMBL3749295 | 0.85 | SIGMAR1 (0.61) | SIGMAR1ACP3HSD17B10CHRM2ADRA1A | |
| SCHEMBL8437895 | 0.85 | SIGMAR1 (0.61) | SIGMAR1ACP3HSD17B10CHRM2ADRA1A | |
| SCHEMBL1200137 | 0.85 | SIGMAR1 (0.61) | SIGMAR1ACP3HSD17B10CHRM2ADRA1A | |
| SCHEMBL30763462 | 0.85 | SIGMAR1 (0.61) | SIGMAR1ACP3HSD17B10CHRM2ADRA1A | |
| SCHEMBL283979 | 0.85 | SIGMAR1 (0.61) | SIGMAR1ACP3HSD17B10CHRM2ADRA1A | |
| Hydrochloric Acid SCHEMBL607712 | 0.82 | SIGMAR1 (0.59) | SIGMAR1ACP3CHRM2ADRA1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL2469805 | 0.82 | SIGMAR1 (0.59) | SIGMAR1ACP3CHRM2ADRA1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL3078151 | 0.82 | SIGMAR1 (0.59) | SIGMAR1ACP3CHRM2ADRA1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8779004-B2 | Stable emulsion formulations | AMGEN, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20070249520-A1 | STABLE EMULSION FORMULATIONS | AMGEN INC. (US) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249520-A1 | STABLE EMULSION FORMULATIONS | CALCR, CALCB, CALCRL | SIGMAR1 172/4885ACP3 166/4885ADRA2C 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.