SCHEMBL5500322

SCHEMBL5500322

CC(Cc1ccc(OCCO)cc1)c1ccc(OCCO)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
ADRB2 P07550 1/20 0.48
ADRB1 P08588 1/20 0.48
ADRB3 P13945 1/20 0.48
NR1I2 O75469 1/20 0.46
ALDH1A1 P00352 4/20 0.46
RECQL P46063 1/20 0.46
CYP3A4 P08684 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTGS2 P35354 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP1 P29466 1/20 0.41
SLCO1B3 Q9NPD5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347086 1.00 ESR1 (0.55) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL347574 0.87 ADRB2 (0.47) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL10608872 0.84 ALDH1A1 (0.50) ADRB2ADRB1ADRB3NR1I2ALDH1A1
SCHEMBL26246228 0.82 ALDH1A1 (0.60) NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2
SCHEMBL1129444 0.82 ADRB2 (0.50) ADRB2ADRB1ADRB3NR1I2ALDH1A1
SCHEMBL10596769 0.82 ESR1 (0.50) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL13077996 0.81 SLC6A4 (0.59) ADRB2ADRB1ADRB3
SCHEMBL10588778 0.81 SLC6A4 (0.59) ADRB2ADRB1ADRB3
SCHEMBL347372 0.80 ALDH1A1 (0.54) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL5551011 0.80 RAB9A (0.54) ADRB2ADRB1ADRB3NR1I2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781238-A1 DENTAL COMPOSITIONS CONTAINING OXIRANE MONOMERS 3M Innovative Properties Company (US) 2007-05-09 EP disclosed
WO-2006019797-A1 DENTAL COMPOSITIONS CONTAINING OXIRANE MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-02-23 WO disclosed
US-6319983-B1 ESTERIFYING (METH)ACRYLIC ACID; REMOVING SOLVENT; REACTING ESTER WITH AN EPOXIDE; REACTING PRODUCT WITH AN ISOCYANATE; NONDISPERSING; FILM HAS IMPROVED HARDNESS, FLEXIBILITY AND/OR CHEMICAL RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
EP-1120396-A2 Process for the preparation of radiation curable acrylates BASF AKTIENGESELLSCHAFT (DE) 2001-08-01 EP disclosed
EP-1043351-A2 Urethane groups containing (meth)acrylic acid esters, process for their preparation and their use as well as radiation-curable coatings containing them BASF AKTIENGESELLSCHAFT (DE) 2000-10-11 EP disclosed
EP-0583953-B1 Bag for bag-in-box KIRIN BREWERY (JP) 2000-05-10 EP disclosed
EP-0583953-A1 Bag for bag-in-box KIRIN BEER KABUSHIKI KAISHA (JP) 1994-02-23 EP disclosed
EP-0415728-A2 Process for preparing blow molded articles MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-03-06 EP disclosed
US-4417011-A UNSATURATED POLYESTER MITSUI TOATSU CHEMICALS, INC. (JP) 1983-11-22 US disclosed