Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21280529 | 0.92 | CA2 (0.37) | CA2RIPK1SLC6A4HTR2AHRH1 | |
| SCHEMBL8694969 | 0.86 | CA2 (0.49) | CA2SLC7A5HTR2A | |
| SCHEMBL5734584 | 0.85 | CA2 (0.40) | CA2SLC6A4 | |
| SCHEMBL6030607 | 0.83 | CA2 (0.37) | CA2RIPK1SLC6A4HTR2AHRH1 | |
| SCHEMBL13871075 | 0.83 | RIPK1 (0.39) | CA2RIPK1SLC6A4HTR2AHRH1 | |
| SCHEMBL8789100 | 0.82 | CA2 (0.41) | CA2 | |
| SCHEMBL14984000 | 0.79 | GSR (0.44) | CA2RIPK1SLC6A4 | |
| SCHEMBL3386535 | 0.79 | TAAR1 (0.41) | CA2SLC6A4HTR2A | |
| SCHEMBL3386536 | 0.79 | TAAR1 (0.41) | CA2SLC6A4HTR2A | |
| SCHEMBL1739510 | 0.79 | GSR (0.44) | CA2RIPK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832576-A1 | 4-Biarylyl-1-phenolyzetidin-2-ones | Microbia Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1682499-B1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | MICROBIA INC (US) | 2007-08-08 | — | — | EP | disclosed |