Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129629 | 0.80 | PKM (0.56) | PKMESR1APOBEC3GALDH1A1NPSR1 | |
| SCHEMBL21034101 | 0.79 | FAAH (0.41) | PKMESR1FAAHPRSS1PRSS2 | |
| SCHEMBL5698632 | 0.78 | PKM (0.43) | PKMESR1FAAHPRSS1PRSS2 | |
| SCHEMBL21034450 | 0.75 | CA12 (0.52) | ALDH1A1CA12CA9CA2KMT2A | |
| SCHEMBL11595292 | 0.74 | PKM (0.50) | PKMESR1APOBEC3GALDH1A1NPSR1 | |
| SCHEMBL1704542 | 0.74 | PKM (0.50) | PKMESR1ALDH1A1NPSR1ALOX15 | |
| SCHEMBL132005 | 0.74 | PKM (0.50) | PKMESR1ALDH1A1NPSR1ALOX15 | |
| SCHEMBL450584 | 0.74 | ESR1 (0.52) | PKMESR1ALDH1A1NPSR1ALOX15 | |
| SCHEMBL10632559 | 0.74 | PKM (0.50) | PKMESR1APOBEC3GALDH1A1NPSR1 | |
| SCHEMBL13096335 | 0.73 | PKM (0.45) | PKMESR1APOBEC3GALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763532-A1 | 1,1'-DIPHOSPHINOFERROCENES HAVING 2,2'-BOUND ACHIRALS OR CHIRAL RADICALS | Solvias AG (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006003196-A1 | 1,1'-DIPHOSPHINOFERROCENES HAVING 2,2'-BOUND ACHIRALS OR CHIRAL RADICALS | SOLVIAS AG (CH) | 2006-01-12 | — | — | WO | disclosed |