Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505503 | 0.80 | ACHE (0.46) | DRD2DRD4DRD3ACHECCR3 | |
| SCHEMBL5500648 | 0.77 | SMN1; SMN2 (0.49) | DRD2DRD4DRD3ACHERECQL | |
| SCHEMBL5505485 | 0.75 | CYP1A2 (0.38) | ADRA2A | |
| SCHEMBL8176219 | 0.73 | MC4R (0.56) | DRD2DRD4DRD3ACHE | |
| SCHEMBL3393340 | 0.73 | MC4R (0.56) | DRD2DRD4DRD3ACHE | |
| SCHEMBL3393342 | 0.73 | MC4R (0.56) | DRD2DRD4DRD3ACHE | |
| SCHEMBL4383178 | 0.70 | DRD2 (0.42) | DRD2DRD4DRD3ACHE | |
| SCHEMBL2691261 | 0.69 | SLC18A2 (0.70) | — | |
| SCHEMBL3395798 | 0.69 | MC4R (0.54) | DRD2DRD4DRD3ACHECCR3 | |
| SCHEMBL3395802 | 0.69 | MC4R (0.54) | DRD2DRD4DRD3ACHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |