Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566263 | 0.82 | GABRA1 (0.46) | ALDH1A1KDM4EMAOBLMNAPOLB | |
| SCHEMBL11281731 | 0.79 | MAOB (0.39) | ALDH1A1KDM4EMAOBLMNAALPL | |
| SCHEMBL110763 | 0.76 | DPP4 (0.50) | ALDH1A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL477452 | 0.76 | MAPT (0.46) | ALDH1A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL9454470 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAOBLMNAPOLB | |
| SCHEMBL7430432 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAOBLMNAPOLB | |
| SCHEMBL5665316 | 0.74 | AKR1B1 (0.48) | ALDH1A1POLBMEN1RECQLKMT2A | |
| SCHEMBL446626 | 0.73 | POLB (0.32) | ALDH1A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL30038773 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL28546393 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794157-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVES | H.Lundbeck A/S (DK) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006032273-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-03-30 | — | — | WO | disclosed |