SCHEMBL477452

SCHEMBL477452

OCc1ccccc1-c1ccco1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.46
ALDH1A1 P00352 7/20 0.46
KDM4E B2RXH2 5/20 0.46
NPC1 O15118 2/20 0.46
OPRM1 P35372 3/20 0.41
OPRD1 P41143 3/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
POLB P06746 5/20 0.39
LMNA P02545 2/20 0.39
MAPK1 P28482 2/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
HPGD P15428 4/20 0.39
ALOX15 P16050 4/20 0.39
CASP1 P29466 4/20 0.39
BLM P54132 3/20 0.39
CASP7 P55210 3/20 0.39
HSD17B10 Q99714 3/20 0.39
PKM P14618 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068990 0.82 PDCD1 (0.56) MAPTALDH1A1KDM4ENPC1OPRM1
SCHEMBL110763 0.80 DPP4 (0.50) MAPTALDH1A1KDM4ENPC1POLB
SCHEMBL9454470 0.80 ALDH1A1 (0.39) MAPTALDH1A1KDM4ENPC1OPRM1
SCHEMBL11281731 0.80 MAOB (0.39) MAPTALDH1A1KDM4ENPC1OPRM1
SCHEMBL7430432 0.80 ALDH1A1 (0.39) MAPTALDH1A1KDM4ENPC1OPRM1
SCHEMBL5665316 0.78 AKR1B1 (0.48) ALDH1A1OPRM1OPRD1POLBMEN1
SCHEMBL28311859 0.77 PTPN1 (0.42) MAPTALDH1A1KDM4ENPC1POLB
SCHEMBL28546393 0.77 ALDH1A1 (0.41) MAPTALDH1A1KDM4ENPC1POLB
SCHEMBL30038773 0.77 ALDH1A1 (0.41) MAPTALDH1A1KDM4ENPC1POLB
SCHEMBL417395 0.76 PRMT6 (0.49) MAPTALDH1A1KDM4ENPC1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066428-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
CN-115066428-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-09-16 CN disclosed
CN-112264089-B SAPO-11 Ni-loaded composite catalyst and preparation method and application thereof 江南大学 2021-11-23 CN disclosed
WO-2021143924-A1 BORIC ACID DERIVATIVE 首药控股(北京)股份有限公司 2021-07-22 WO disclosed
CN-112264089-A SAPO-11 Ni-loaded composite catalyst and preparation method and application thereof 江南大学 2021-01-26 CN disclosed
US-8563786-B2 Method for producing optically active alcohol MITSUI CHEMICALS, INC. (JP) 2013-10-22 US disclosed
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-04-12 US disclosed
EP-2412694-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed
US-6211374-B1 REVERSE COLOR CHANGE; DISPLAYING IPPOLITI JOSEPH THOMAS (US) 2001-04-03 US disclosed
US-4246178-A CHEMICAL INTERMEDIATE FOR THE FLAVOR MALTOL SHIN-ETSU CHEMICAL CO., LTD. (JP) 1981-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1A, ADH1C, FHIT MAPT 898/4885ALDH1A1 62/4885KDM4E 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.