SCHEMBL5501304

SCHEMBL5501304

Cc1cc(F)ccc1C1CC(=O)CCN1C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2486149 0.89 TACR1 (0.41) TACR1
SCHEMBL2484442 0.89 TACR1 (0.41) TACR1
SCHEMBL2484439 0.89 TACR1 (0.41) TACR1
SCHEMBL3163726 0.83 GHSR (0.41) TACR1
SCHEMBL3163732 0.83 GHSR (0.41) TACR1
SCHEMBL27604482 0.83 MTNR1B (0.34)
SCHEMBL5218238 0.82 TACR1 (0.53) TACR1
SCHEMBL12968150 0.82 TACR1 (0.38) TACR1
SCHEMBL2488624 0.78 PARP1 (0.46)
SCHEMBL4859941 0.78 PARP1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513814-A4 NOVEL PIPERIDINE COMPOUND TANABE SEIYAKU CO (JP) 2007-03-14 EP disclosed
EP-1513814-A1 NOVEL PIPERIDINE COMPOUND TANABE SEIYAKU CO., LTD. (JP) 2005-03-16 EP disclosed
WO-2003099787-A1 NOVEL PIPERIDINE COMPOUND TANABE SEIYAKU CO., LTD. (JP) 2003-12-04 WO disclosed