Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	3/20	0.57

▸	MTOR	P42345	2/20	0.57

▸	ALDH1A1	P00352	2/20	0.57

▸	THRB	P10828	1/20	0.57

▸	MDM2	Q00987	1/20	0.57

▸	NCOA1	Q15788	1/20	0.57

▸	NCOA3	Q9Y6Q9	1/20	0.57

▸	GMNN	O75496	1/20	0.57

▸	TP53	P04637	1/20	0.57

▸	NFKB1	P19838	1/20	0.57

▸	DNMT1	P26358	1/20	0.57

▸	THPO	P40225	1/20	0.57

▸	HTT	P42858	1/20	0.57

▸	RAB9A	P51151	1/20	0.57

▸	BLM	P54132	1/20	0.57

▸	HBB	P68871	1/20	0.57

▸	PMP22	Q01453	1/20	0.57

▸	PYGM	P11217	1/20	0.53

▸	SMN1; SMN2	Q16637	2/20	0.48

▸	POLB	P06746	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL20240168	1.00	LMNA (0.57)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL19657184	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL2583859	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL12937913	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL770112	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL6297249	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL770113	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL12230437	0.95	LMNA (0.62)	LMNAMTORALDH1A1THRBMDM2
SCHEMBL27936168	0.87	LMNA (0.58)	LMNAMTORALDH1A1THRBMDM2
Phosphoric Acid SCHEMBL14661092	0.86	LMNA (0.57)	LMNAMTORALDH1A1THRBMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0828750-B1	PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE	EC TECHNOLOGY LLC (US)	2013-07-17	—	—	EP	disclosed
EP-0828750-A4	PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE	EC TECHNOLOGY LLC (US)	2007-11-07	—	—	EP	disclosed
US-5945527-A	REACTING CYTOSINE CONTAINING A LEAVING GROUP ATTACHED TO 5- OR 6-POSTION OF MOLECULE, ISOLATING MODIFIED NUCLEOSIDE; FOR NOVEL FUNGICIDES, VIRICIDES, BACTERICIDES, ANTITUMOR AGENTS	NEXSTAR PHARMACEUTICALS, INC. (US)	1999-08-31	—	—	US	disclosed
EP-0828750-A1	PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE	NeXstar Pharmaceuticals, Inc. (US)	1998-03-18	—	—	EP	disclosed
WO-1996038460-A1	PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE	NEXSTAR PHARMACEUTICALS, INC. (US)	1996-12-05	—	—	WO	disclosed