SCHEMBL5501440

SCHEMBL5501440

NC(Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1I)C(=O)O.[NaH]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 5/20 0.70
THRB P10828 9/20 0.54
THRA P10827 6/20 0.54
LMNA P02545 4/20 0.54
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
PPARG P37231 3/20 0.54
CYP2D6 P10635 1/20 0.54
TSHR P16473 1/20 0.54
GABRP O00591 1/20 0.54
GABRD O14764 1/20 0.54
ABCB11 O95342 1/20 0.54
F2 P00734 1/20 0.54
GABRA1 P14867 1/20 0.54
GABRB1 P18505 1/20 0.54
GABRG2 P18507 1/20 0.54
GABRB3 P28472 1/20 0.54
ADORA1 P30542 1/20 0.54
GABRA5 P31644 1/20 0.54
GABRA3 P34903 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31368013 0.99 PCNA (0.71) PCNATHRBTHRALMNAMEN1
SCHEMBL34943 0.99 PCNA (0.71) PCNATHRBTHRALMNAMEN1
SCHEMBL2679290 0.98 PCNA (0.70) PCNATHRBTHRALMNAMEN1
Sulfuric Acid SCHEMBL2513306 0.95 PCNA (0.67) PCNATHRBTHRALMNAMEN1
SCHEMBL4439595 0.84 PCNA (0.97) PCNATHRBTHRALMNAMEN1
SCHEMBL2575598 0.82 PCNA (0.64) PCNATHRBTHRALMNAMEN1
SCHEMBL1487713 0.82 PCNA (1.00) PCNATHRBTHRALMNAMEN1
SCHEMBL428139 0.82 PCNA (1.00) PCNATHRBTHRALMNAMEN1
SCHEMBL445767 0.82 PCNA (1.00) PCNATHRBTHRALMNAMEN1
SCHEMBL4926016 0.82 PCNA (0.52) PCNATHRBTHRALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038285-A Kit and method for constructing human bone organ by using pluripotent stem cells 广东医科大学附属医院 2026-05-15 CN claimed
CN-118480508-A Culture medium capable of increasing expression of CD11b by THP-1 cells 上海源培生物科技股份有限公司 2024-08-13 CN claimed
CN-102858156-A Methods, compositions and kits for providing therapy ASHUR-FABIAN OSNAT 2013-01-02 CN claimed
CN-102625689-A Method and composition for restoration of age-related tissue loss in the face or selected areas of the body NEOSTEM INC 2012-08-01 CN claimed
CN-1156591-A Oxytocic aid for fishes and hasten parturition method thereof QIAN JIADA (CN) 1997-08-13 CN claimed
CN-1127634-A Controlled release hormone microsphere injection and preparing method thereof CHENGDU ORGANIC CHEM INST (CN) 1996-07-31 CN claimed
CN-1126589-A Injecta of delayed hormone microcapsule and its prepn CHENGDU ORGANIC CHEM INST (CN) 1996-07-17 CN claimed
CN-122038285-A Kit and method for constructing human bone organ by using pluripotent stem cells 广东医科大学附属医院 2026-05-15 CN disclosed
CN-118480508-A Culture medium capable of increasing expression of CD11b by THP-1 cells 上海源培生物科技股份有限公司 2024-08-13 CN disclosed
EP-4301357-A1 THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS Terns Pharmaceuticals, Inc. (US) 2024-01-10 EP disclosed
WO-2023072170-A1 A METHOD FOR PROMOTING THE DIFFERENTIATION OF STEM CELLS INTO FUNCTIONALLY MATURE ISLET β CELLS AND USE THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2023-05-04 WO disclosed
WO-2022187403-A1 THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS TERNS PHARMACEUTICALS, INC. (US) 2022-09-09 WO disclosed
CN-114891070-A Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-08-12 CN disclosed
US-6143717-A ADMINISTERING TO IMMUNOSUPPRESSED MAMMAL INSULIN, GLUCOSE, AND POTASSIUM FOR IMMUNOENHANCEMENT HILL MEDICAL CORPORATION (US) 2000-11-07 US disclosed
CN-1223659-A Fused imidazopyridine derivatives as antihyperlipidemic agents TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-07-21 CN disclosed
US-5840770-A IMMUNOENHANCEMENT OR IMMUNE-POTENTIATION THERAPY COMPRISING ADMINISTRATION OF POTASSIUM, INSULIN, GLUCOSE AND OPTIONALLY, THYROID, A CHOLINERGIC AGENT AND BICARBONATE HILL MEDICAL CORPORATION (US) 1998-11-24 US disclosed
CN-1156591-A Oxytocic aid for fishes and hasten parturition method thereof QIAN JIADA (CN) 1997-08-13 CN disclosed
CN-1128657-A Composition for anti hypertriglyceridemia TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-08-14 CN disclosed
CN-1127634-A Controlled release hormone microsphere injection and preparing method thereof CHENGDU ORGANIC CHEM INST (CN) 1996-07-31 CN disclosed
CN-1126589-A Injecta of delayed hormone microcapsule and its prepn CHENGDU ORGANIC CHEM INST (CN) 1996-07-17 CN disclosed