Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501615 | 1.00 | GAA (0.32) | GAAMAPTP2RX4 | |
| SCHEMBL4471450 | 0.80 | GAA (0.32) | GAAMAPTP2RX4 | |
| SCHEMBL4471457 | 0.80 | GAA (0.32) | GAAMAPTP2RX4 | |
| SCHEMBL4462510 | 0.67 | GAA (0.31) | GAAMAPT | |
| SCHEMBL4462506 | 0.67 | GAA (0.31) | GAAMAPT | |
| SCHEMBL5504074 | 0.64 | HTR6 (0.34) | — | |
| SCHEMBL5504078 | 0.64 | HTR6 (0.34) | — | |
| SCHEMBL4465969 | 0.58 | PSIP1 (0.36) | GAAMAPT | |
| SCHEMBL4465966 | 0.58 | PSIP1 (0.36) | GAAMAPT | |
| SCHEMBL4477020 | 0.56 | GAA (0.41) | GAAMAPTP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778669-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006023931-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| EP-1778669-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006023931-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-03-02 | — | — | WO | disclosed |