Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504074 | 1.00 | HTR6 (0.34) | HTR6 | |
| SCHEMBL4459243 | 0.83 | HTR6 (0.36) | HTR6 | |
| SCHEMBL4459250 | 0.83 | HTR6 (0.36) | HTR6 | |
| SCHEMBL5501615 | 0.64 | GAA (0.32) | — | |
| SCHEMBL5501620 | 0.64 | GAA (0.32) | — | |
| SCHEMBL10433225 | 0.61 | HTR6 (0.58) | HTR6 | |
| SCHEMBL12994630 | 0.61 | FABP4 (0.51) | HTR6 | |
| SCHEMBL4474572 | 0.58 | BRD4 (0.38) | — | |
| SCHEMBL4474579 | 0.58 | BRD4 (0.38) | — | |
| SCHEMBL4465969 | 0.58 | PSIP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778669-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006023931-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| EP-1778669-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006023931-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-03-02 | — | — | WO | disclosed |