SCHEMBL5501891

SCHEMBL5501891

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 6/20 0.55
▸ MC4R P32245 7/20 0.55
▸ IL23R Q5VWK5 2/20 0.50
▸ NPBWR1 P48145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5498316 0.97 KISS1R (0.55) KISS1RMC4RIL23RNPBWR1
SCHEMBL14811912 0.94 MC4R (0.57) KISS1RMC4RNPBWR1
SCHEMBL5498747 0.93 KISS1R (0.62) KISS1RMC4RIL23RNPBWR1
SCHEMBL5499557 0.90 KISS1R (0.61) KISS1RIL23RNPBWR1
SCHEMBL5990130 0.89 KISS1R (0.59) KISS1RMC4RIL23RNPBWR1
SCHEMBL30264577 0.89 MC4R (0.52) KISS1RMC4RIL23R
SCHEMBL22339063 0.89 MC4R (0.53) KISS1RMC4RNPBWR1
SCHEMBL22339064 0.88 MC4R (0.55) KISS1RMC4RNPBWR1
SCHEMBL29420167 0.88 MC4R (0.64) KISS1RMC4R
SCHEMBL12057583 0.88 MC4R (0.64) KISS1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7307063-B2 Melanocortin metallopeptides for treatment of sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2007-12-11 — — US disclosed
WO-2002064091-A2 MELANOCORTIN METALLOPEPTIDES FOR TREATMENT OF SEXUAL DYSFUNCTION PALATIN TECHNOLOGIES, INC. (US) 2002-08-22 — — WO disclosed
Send feedback