SCHEMBL22339064

SCHEMBL22339064

COc1ccc(CCCC(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 8/20 0.55
▸ CCKBR P32239 3/20 0.54
▸ KISS1R Q969F8 3/20 0.53
▸ NPBWR1 P48145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14811912 0.94 MC4R (0.57) MC4RCCKBRKISS1RNPBWR1
SCHEMBL22339063 0.90 MC4R (0.53) MC4RCCKBRKISS1RNPBWR1
SCHEMBL22485392 0.89 MC4R (0.54) MC4RCCKBRKISS1RNPBWR1
SCHEMBL5501891 0.88 KISS1R (0.55) MC4RKISS1RNPBWR1
SCHEMBL22485206 0.87 MC4R (0.50) MC4RCCKBRKISS1RNPBWR1
SCHEMBL5498316 0.87 KISS1R (0.55) MC4RKISS1RNPBWR1
SCHEMBL22339065 0.87 CCKBR (0.63) MC4RCCKBRKISS1R
SCHEMBL29420167 0.87 MC4R (0.64) MC4RKISS1R
SCHEMBL12057583 0.87 MC4R (0.64) MC4RKISS1R
SCHEMBL22485368 0.87 MC4R (0.50) MC4RCCKBRKISS1RNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3704134-B1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS BV (NL) 2021-12-22 — — EP disclosed
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS B.V. (NL) 2020-10-01 — — US disclosed
WO-2020161255-A1 NOVEL METHOD FOR REDUCING HAIR GROWTH DSM IP ASSETS B.V. (NL) 2020-08-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES VIP, CLPP, SGTA MC4R 1528/4885CCKBR 2568/4885KISS1R 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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