Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61947 | 0.72 | AR (0.46) | ARPGR | |
| SCHEMBL91097 | 0.64 | AR (0.46) | ARPGR | |
| SCHEMBL15392969 | 0.64 | NR1H2 (0.36) | ARPGR | |
| SCHEMBL16530109 | 0.59 | HTR6 (0.39) | ARPGR | |
| SCHEMBL29952669 | 0.59 | ENPP2 (0.35) | ENPP2 | |
| SCHEMBL2002285 | 0.56 | AR (0.54) | ARPGR | |
| SCHEMBL24828300 | 0.55 | LRRK2 (0.32) | — | |
| SCHEMBL91095 | 0.53 | — | — | |
| SCHEMBL29957036 | 0.52 | ENPP2 (0.44) | ENPP2 | |
| Benzonitrile SCHEMBL28017673 | 0.52 | TSHR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776107-A1 | PROGESTERONE RECEPTOR MODULATORS COMPRISING PYRROLE-OXINDOLE DERIVATIVES AND USES THEREOF | Wyeth (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006023109-A1 | PROGESTERONE RECEPTOR MODULATORS COMPRISING PYRROLE-OXINDOLE DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-03-02 | — | — | WO | disclosed |