Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | APEH | P13798 | 1/20 | 0.31 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954478 | 0.76 | PPME1 (0.48) | HTR6APEHPPME1RAPGEF4 | |
| SCHEMBL29512049 | 0.72 | HTR6 (0.38) | ENPP2HTR6APEHPPME1RAPGEF4 | |
| SCHEMBL15155241 | 0.70 | HTR6 (0.39) | HTR6APEHPPME1RAPGEF4 | |
| SCHEMBL5776603 | 0.68 | HTR6 (0.38) | HTR6APEHPPME1RAPGEF4 | |
| SCHEMBL20524816 | 0.68 | ALDH1A1 (0.40) | — | |
| SCHEMBL2465489 | 0.68 | RAPGEF4 (0.41) | HTR6APEHPPME1RAPGEF4 | |
| SCHEMBL28125877 | 0.68 | POLB (0.41) | HTR6APEHPPME1 | |
| SCHEMBL15176440 | 0.68 | BAZ2B (0.40) | HTR6APEHPPME1 | |
| SCHEMBL317152 | 0.67 | — | — | |
| SCHEMBL28125964 | 0.67 | LMNA (0.39) | HTR6APEHPPME1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |