SCHEMBL5502033

SCHEMBL5502033

O=S(=O)(O)c1[c]ccc(Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
CYP2C9 P11712 1/20 0.32
ALDH1A1 P00352 4/20 0.31
PARP1 P09874 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
S100A4 P26447 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
RECQL P46063 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KIF18A Q8NI77 1/20 0.30
FLT1 P17948 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2169120 0.79 CA1 (0.40) MEN1KMT2AMAPT
SCHEMBL751917 0.79 CCR2 (0.34) S100A4LMNAMAPTKIF18A
SCHEMBL4745042 0.77 LMNA (0.38) TSHRALDH1A1LMNAHPGDHSD17B10
SCHEMBL1373270 0.77 ALDH1A1 (0.41) TSHRCYP2C9ALDH1A1TDP1LMNA
SCHEMBL27993120 0.76 DDR1 (0.36) MEN1KMT2ALMNAMAPTHTT
SCHEMBL20838953 0.76 ALDH1A1 (0.35) TSHRALDH1A1TDP1LMNAHSD17B10
SCHEMBL10439981 0.75 CA12 (0.33) S100A4
SCHEMBL2152786 0.75 ALDH1A1 (0.44) TSHRCYP2C9ALDH1A1TDP1MEN1
SCHEMBL1374635 0.75 SNCA (0.35) HSD17B10
SCHEMBL28057658 0.75 PARP1 (0.35) TSHRALDH1A1PARP1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1354007-B1 SINGLE-PHASE MIXED CRYSTALS OF LAKED MONOAZO DYES CIBA SC HOLDING AG (CH) 2007-02-14 EP disclosed
US-6913640-B2 Single-phase mixed crystals of laked monoazo dyes CIBA SPECIALTY CHEMICALS (US) 2005-07-05 US disclosed
US-20040087781-A1 Single-phase mixed crystals of laked monoazo dyes CIBA SPECIALTY CHEMICALS CORP. 2004-05-06 US disclosed
EP-1354007-A1 SINGLE-PHASE MIXED CRYSTALS OF LAKED MONOAZO DYES Ciba SC Holding AG (CH) 2003-10-22 EP disclosed
WO-2002059217-A1 SINGLE-PHASE MIXED CRYSTALS OF LAKED MONOAZO DYES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-08-01 WO disclosed
US-5677433-A FOR TEXTILES, LEATHER, PAPER ZENECA LIMITED (GB) 1997-10-14 US disclosed
EP-0743968-A1 ORGANIC CHEMICALS BASF AKTIENGESELLSCHAFT (DE) 1996-11-27 EP disclosed
WO-1995021892-A1 ORGANIC CHEMICALS ZENECA LIMITED (GB) 1995-08-17 WO disclosed
EP-0395207-A1 New reactive dyes ZENECA LIMITED (GB) 1990-10-31 EP disclosed
EP-0385426-A1 Water soluble reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-05 EP disclosed
EP-0368356-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP disclosed
EP-0354409-A1 Fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-14 EP disclosed
US-4806640-A Triphendioxazine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1989-02-21 US disclosed
EP-0204245-B1 REACTIVE DYES BAYER AG (DE) 1988-12-21 EP disclosed
EP-0111830-B1 WATER SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-01 EP disclosed
EP-0204245-A2 Reactive dyes BAYER AG (DE) 1986-12-10 EP disclosed
EP-0111830-A2 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-27 EP disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 EP disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed