Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28923502 | 0.98 | DRD2 (0.45) | DRD2DRD4MAPTALDH1A1AR | |
| Hydrochloric Acid SCHEMBL30142473 | 0.98 | DRD2 (0.45) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL2217869 | 0.86 | MAPT (0.45) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL17937412 | 0.85 | MAPT (0.40) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL23384713 | 0.83 | ALDH1A1 (0.53) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL30964480 | 0.83 | HTR2A (0.47) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL5827521 | 0.83 | HTR2A (0.47) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL30727376 | 0.83 | ALDH1A1 (0.53) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL6101285 | 0.83 | ALDH1A1 (0.49) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL8527251 | 0.83 | DRD2 (0.41) | DRD2DRD4MAPTALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605089-A1 | COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K | Mekanistic Therapeutics LLC (US) | 2025-08-27 | — | — | EP | disclosed |
| US-20250019380-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2025-01-16 | — | — | US | disclosed |
| CN-118791417-A | Pink back pteridonic acid derivative, preparation method and application thereof | 安徽工业大学 | 2024-10-18 | — | — | CN | disclosed |
| EP-3858811-B1 | N-AROMATIC AMIDES COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2024133499-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) | 2024-06-27 | — | — | WO | disclosed |
| EP-4370124-A1 | PI3Ka INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024086296-A1 | COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K | MEKANISTIC THERAPEUTICS LLC (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | SHENZHEN EDK PHARMACEUTICAL TECH CO LTD (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20110195954-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20110021500-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| US-20110021500-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| US-20110021500-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| WO-2011001114-A1 | NOVEL (6-OXO-1, 6-DIHYDRO-PYRIMIDIN-2-YL)-AMIDE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL USE THEREOF AS AKT(PKB) PHOSPHORYLATION INHIBITORS | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | WO | disclosed |
| EP-2251338-A2 | Organic compounds | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251339-A2 | COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251339-A2 | COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009065920-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009065919-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021500-A1 | NOVEL COMPOUNDS | CALCRL, CALCR, CALCA | DRD2 640/4885DRD4 694/4885MAPT 797/4885 |
| US-20250019380-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | PIK3CA, PIK3CB, PIK3CD | DRD2 4864/4885DRD4 4854/4885MAPT 3881/4885 |
| US-20230382870-A1 | N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | H1-3, H1-0, NAT1 | DRD2 291/4885DRD4 379/4885MAPT 1983/4885 |
| US-20110195954-A1 | NOVEL COMPOUNDS | CALCRL, CALCR, CALCA | DRD2 738/4885DRD4 784/4885MAPT 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.