SCHEMBL5502149

SCHEMBL5502149

C=CC[Si](CC=C)(CC=C)CS(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2211339 0.69
SCHEMBL235304 0.67 TSHR (0.33)
SCHEMBL2187547 0.65
SCHEMBL17201496 0.65 TSHR (0.31)
SCHEMBL8064324 0.64 TSHR (0.41)
SCHEMBL13610 0.64
SCHEMBL670675 0.62
SCHEMBL4779247 0.62
Phosphonic Acid SCHEMBL2172715 0.62
SCHEMBL175498 0.62 ABCC4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747209-A4 A FACILE METHOD FOR SYNTHESIZING BACCATIN III COMPOUNDS IMMUNOGEN INC (US) 2007-12-12 EP disclosed
US-7186851-B2 Facile method for synthesizing baccatin III compounds IMMUNOGEN, INC. (US) 2007-03-06 US disclosed
EP-1747209-A1 A FACILE METHOD FOR SYNTHESIZING BACCATIN III COMPOUNDS Immunogen, Inc. (US) 2007-01-31 EP disclosed
WO-2005113528-A1 A FACILE METHOD FOR SYNTHESIZING BACCATIN III COMPOUNDS IMMUNOGEN, INC. (US) 2005-12-01 WO disclosed
US-20050256323-A1 Facile method for synthesizing baccatin III compounds IMMUNOGEN, INC. 2005-11-17 US disclosed