Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801722 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL6828843 | 0.73 | LMNA (0.40) | LMNAALOX15 | |
| SCHEMBL2875011 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL4563837 | 0.72 | MCL1 (0.32) | MAPTLMNA | |
| SCHEMBL235304 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL1937403 | 0.69 | ABCC4 (0.55) | ABCC4MAPTLMNAALOX15HSD17B10 | |
| SCHEMBL1937334 | 0.69 | ABCC4 (0.55) | ABCC4MAPTLMNAALOX15HSD17B10 | |
| SCHEMBL7770882 | 0.67 | LMNA (0.35) | ABCC4MAPTLMNAALOX15HSD17B10 | |
| SCHEMBL1101342 | 0.67 | LMNA (0.35) | ABCC4MAPTLMNA | |
| SCHEMBL17201496 | 0.66 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355826-B1 | Modified poly(organo-organopolysiloxanes) with a comb or block structure, and process for their preparation | WACKER CHEMIE GMBH (DE) | 1994-02-09 | — | — | EP | claimed |
| US-8153705-B2 | Silyl esters, their use in binder systems and paint compositions and a process for production thereof | SIGMAKALON B.V. (NL) | 2012-04-10 | — | — | US | disclosed |
| US-8148446-B2 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | SIGMAKALON B.V. (NL) | 2012-04-03 | — | — | US | disclosed |
| EP-1608716-B8 | PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES | PPG BV (NL) | 2012-03-07 | — | — | EP | disclosed |
| EP-1608716-B1 | PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES | SIGMAKALON B V (NL) | 2011-11-16 | — | — | EP | disclosed |
| US-20110263605-A1 | Azabicyclo[2.2.1]Heptane Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | BRISTOL-MYERS SQUIBB COMPANY | 2011-10-27 | — | — | US | disclosed |
| US-7902313-B2 | Process for the preparation of poly(silyl ester)s, and their uses | SIGMAKALON B.V. (NL) | 2011-03-08 | — | — | US | disclosed |
| US-20100249298-A1 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | GILLARD MICHEL | 2010-09-30 | — | — | US | disclosed |
| US-20070161722-A1 | Silyl Esters, Their Use in Binder Systems and Paint Compositions and a Process for Production Thereof | SIGMA COATINGS B.V. (NL) | 2007-07-12 | — | — | US | disclosed |
| EP-1427736-B1 | PROCESS FOR THE PREPARATION OF ORGANOSILYLATED CARBOXYLATE MONOMERS, AND THEIR USE IN ANTIFOULING COATINGS | SIGMA COATINGS BV (NL) | 2006-11-15 | — | — | EP | disclosed |
| WO-2004099326-A2 | SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF | SIGMAKALON B.V. (NL) | 2004-11-18 | — | — | WO | disclosed |
| EP-1475415-A1 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | SigmaKalon Services B.V. (NL) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004085560-A1 | PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES | SIGMAKALON B.V. (NL) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085518-A1 | A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS | SIGMAKALON B.V. (NL) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085502-A1 | A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN | SIGMAKALON B.V. (NL) | 2004-10-07 | — | — | WO | disclosed |
| EP-1462467-A1 | A process for the production of silyl group containing polymer resin | Sigma Kalon Services B.V. (NL) | 2004-09-29 | — | — | EP | disclosed |
| EP-1462472-A1 | A process for the protection of acid groups in polymers | Sigma Kalon Services B.V. (NL) | 2004-09-29 | — | — | EP | disclosed |
| EP-1427736-A1 | PROCESS FOR THE PREPARATION OF ORGANOSILYLATED CARBOXYLATE MONOMERS, AND THEIR USE IN ANTIFOULING COATINGS | SIGMA COATINGS B.V. (NL) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003027124-A1 | PROCESS FOR THE PREPARATION OF ORGANOSILYLATED CARBOXYLATE MONOMERS, AND THEIR USE IN ANTIFOULING COATINGS | SIGMA COATINGS B.V. (NL) | 2003-04-03 | — | — | WO | disclosed |
| EP-1295888-A1 | Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings | SIGMA COATINGS B.V. (NL) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263605-A1 | Azabicyclo[2.2.1]Heptane Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | CHRNA7, CHRNA2, CHRNA5 | ABCC4 2753/4885MAPT 290/4885LMNA 2732/4885 |
| US-20100249298-A1 | Silyl esters, their use in binder systems and paint compositions and a process of production thereof | LCT, PCMT1, TST | ABCC4 1899/4885MAPT 176/4885LMNA 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.