SCHEMBL2482965

SCHEMBL2482965

O=C(O)c1cc(Br)ccc1-c1ccc(Br)cc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.63
GLA P06280 1/20 0.63
MYC P01106 1/20 0.52
NR4A1 P22736 1/20 0.52
CES2 O00748 1/20 0.50
GALR3 O60755 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
GPR35 Q9HC97 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
CASP1 P29466 1/20 0.50
CYP2C19 P33261 1/20 0.50
APEX1 P27695 1/20 0.49
AKR1C3 P42330 4/20 0.48
AKR1C2 P52895 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30219515 1.00 KDM4E (0.63) KDM4EGLAMYCNR4A1CES2
SCHEMBL12203704 0.88 KDM4E (0.52) KDM4EGLAMYCNR4A1CES2
SCHEMBL10026168 0.87 HSD17B10 (0.58) KDM4EGLAMYCNR4A1CES2
SCHEMBL31327315 0.87 HSD17B10 (0.58) KDM4EGLAMYCNR4A1CES2
Hydrochloric Acid SCHEMBL20943641 0.86 HSD17B10 (0.56) KDM4EGLAMYCNR4A1GRIN1
SCHEMBL1982514 0.86 AKR1C3 (0.64) KDM4EGLAAKR1C3AKR1C2AKR1C1
SCHEMBL618056 0.83 KDM4E (0.65) KDM4EGLAMYCNR4A1CES2
SCHEMBL16491965 0.82 DHODH (0.47) KDM4EGLAAKR1C3AKR1C2AKR1C1
SCHEMBL16267089 0.81 SORT1 (0.51) KDM4EGLAMYCNR4A1ALOX15
SCHEMBL10058717 0.81 ACLY (0.50) KDM4EGLAMYCNR4A1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US disclosed
US-10069082-B2 Organic electroluminescent compounds and organic optoelectronic devices comprising the same Shanghai Tianma AM-OLED Co., Ltd. (CN) 2018-09-04 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
EP-3315531-A1 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY Xiamen Sinopeg Biotech Co., Ltd. (CN) 2018-05-02 EP disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
US-9761820-B2 Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-09-12 US disclosed
US-9761820-B2 Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-09-12 US disclosed
US-20170148996-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) 2017-05-25 US disclosed
US-7462683-B2 Dihalide, polymer compound and method for producing the same TOKYO INSTITUTE OF TECHNOLOGY (JP) 2008-12-09 US disclosed
US-20070185306-A1 Dihalide, polymer compound and method for producing the same TOKYO INSTITUTE OF TECHNOLOGY (JP) 2007-08-09 US disclosed
US-20070185306-A1 Dihalide, polymer compound and method for producing the same TOKYO INSTITUTE OF TECHNOLOGY (JP) 2007-08-09 US disclosed
US-20070034832-A1 (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-02-15 US disclosed
US-20070034832-A1 (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-02-15 US disclosed
EP-1717258-A1 DIHALIDE, POLYMER COMPOUND AND METHOD FOR PRODUCING SAME Tokyo Institute of Technology (JP) 2006-11-02 EP disclosed
US-5344896-A Alkylsulfonate-containing polymers from tetraaminobenzene and benzothiazole-substituted terephthalic acids THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1994-09-06 US disclosed
US-5312876-A Copolybenzobisthiazoles and benzobisoxazoles with benzimidazoles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1994-05-17 US disclosed
US-5081256-A Para ordered aromatic diacids containing benzimidazole groups UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1992-01-14 US disclosed
US-5081256-A Para ordered aromatic diacids containing benzimidazole groups UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1992-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A KDM4E 3245/4885GLA 1647/4885MYC 2092/4885
US-20070185306-A1 Dihalide, polymer compound and method for producing the same HSPA4L, HDHD5, MRPL21 KDM4E 3956/4885GLA 2762/4885MYC 1436/4885
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 KDM4E 3210/4885GLA 1614/4885MYC 2164/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 KDM4E 2604/4885GLA 1337/4885MYC 2056/4885
US-10069082-B2 Organic electroluminescent compounds and organic optoelectronic devices comprising the same OR10J3, PPOX, OR51E2 KDM4E 2416/4885GLA 2541/4885MYC 1936/4885
US-20170148996-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME OR10J3, PPOX, OR51E2 KDM4E 2416/4885GLA 2541/4885MYC 1936/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 KDM4E 4115/4885GLA 1838/4885MYC 3726/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 KDM4E 4115/4885GLA 1838/4885MYC 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.