⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678107 | 0.70 | SIGMAR1 (0.33) | — | |
| SCHEMBL11677852 | 0.67 | ALDH1A1 (0.30) | — | |
| Bicarbonate SCHEMBL7732730 | 0.66 | EPHX1 (0.35) | — | |
| SCHEMBL5737366 | 0.65 | — | — | |
| SCHEMBL5737498 | 0.65 | — | — | |
| SCHEMBL985887 | 0.65 | — | — | |
| SCHEMBL5734363 | 0.65 | — | — | |
| SCHEMBL5735985 | 0.65 | — | — | |
| SCHEMBL5249332 | 0.63 | SIGMAR1 (0.34) | — | |
| SCHEMBL15937107 | 0.63 | GRIN2D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765287-A2 | IMMEDIATE RELEASE FORMULATIONS OF MEMANTINE ORAL DOSAGE FORMS | Merz Pharma GmbH & Co. KGaA (DE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006096194-A2 | DRINKABLE IMMEDIATE RELEASE TABLET MADE WITH DIRECT COMPRESSION OF MEMANTINE OR NERAMEXANE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-09-14 | — | — | WO | disclosed |