Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17725848 | 0.96 | MAPK14 (0.50) | NOTUMTAAR1MAPK14MAPK13RAF1 | |
| Pyridine SCHEMBL27859679 | 0.85 | NPC1 (0.50) | NOTUMTAAR1MAPK14MAPK13RAF1 | |
| SCHEMBL15411832 | 0.83 | NOTUM (0.68) | NOTUMPRKCIKIF11CNR1LMNA | |
| SCHEMBL16394285 | 0.83 | TAAR1 (0.71) | TAAR1ALOX5MAOBMAP4K4 | |
| SCHEMBL31491189 | 0.83 | TAAR1 (0.71) | TAAR1ALOX5MAOBMAP4K4 | |
| SCHEMBL817554 | 0.83 | ALOX5 (0.65) | NOTUMTAAR1ALOX5MAOBIDO1 | |
| SCHEMBL31222672 | 0.83 | ALOX5 (0.65) | NOTUMTAAR1ALOX5MAOBIDO1 | |
| SCHEMBL23626070 | 0.82 | MAPK14 (0.49) | NOTUMMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL18134356 | 0.82 | CYP19A1 (0.50) | MAPK14MAPK13RAF1MAPK12MAPK11 | |
| Pyrimidine SCHEMBL27936731 | 0.81 | NPC1 (0.50) | NOTUMTAAR1MAPK14MAPK13RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110642-B2 | Synthesis of vinylphenylpyridine and living anionic polymerization | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-02-07 | — | — | US | disclosed |
| US-20090105416-A1 | Synthesis of Vinylphenylpyridine and Living Anionic Polymerization | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-04-23 | — | — | US | disclosed |
| WO-2007129810-A1 | SYNTHESIS OF VINYLPHENYLPYRIDINE AND LIVING ANIONIC POLYMERIZATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-11-15 | — | — | WO | disclosed |
| US-4727148-A | Certain aromatization process for preparing 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4604467-A | Certain 4-(3,4-dibromocyclohexyl)pyridines | ETHYL CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4552964-A | 4-(1-Chlorocyclohex-3-enyl)pyridines and preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| US-4552963-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid | ETHYL CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| US-4550167-A | Preparation of 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| US-4533735-A | Process for preparing antibacterial compounds | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| US-4490535-A | 4-(3- and 4-Chlorocyclohex-3-enyl)pyridine intermediates | ETHYL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| US-4405792-A | Substituted pyridines and their preparation | ETHYL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105416-A1 | Synthesis of Vinylphenylpyridine and Living Anionic Polymerization | PBRM1, MVD, PCBP1 | NOTUM 1094/4885TAAR1 4360/4885MAPK14 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.