Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 9/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503809 | 0.86 | RBP4 (0.46) | RBP4OPRL1DRD3CXCR2DRD1 | |
| SCHEMBL2784637 | 0.84 | DRD3 (0.42) | RBP4OPRL1DRD3GRM2 | |
| SCHEMBL2785344 | 0.83 | DRD3 (0.43) | RBP4OPRL1DRD3GRM2 | |
| SCHEMBL5503228 | 0.82 | DRD2 (0.43) | RBP4DRD3CXCR2 | |
| SCHEMBL5503775 | 0.82 | DRD2 (0.43) | RBP4DRD3CXCR2 | |
| SCHEMBL3774468 | 0.81 | OPRL1 (0.43) | RBP4OPRL1DRD1KDM4EPKM | |
| SCHEMBL5513017 | 0.80 | DRD2 (0.37) | DRD3GRM2UBE2MDCUN1D1 | |
| SCHEMBL5505250 | 0.80 | DRD2 (0.37) | DRD3GRM2 | |
| SCHEMBL2782945 | 0.80 | RBP4 (0.41) | RBP4DRD3GRM2 | |
| SCHEMBL3765897 | 0.80 | DRD3 (0.46) | RBP4DRD3GRM2KDM4EUBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768958-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-04 | — | — | EP | claimed |
| WO-2005121088-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |