Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505250 | 0.95 | DRD2 (0.37) | DRD2SLC6A4HTR2CHTR7HTR2B | |
| SCHEMBL2784637 | 0.81 | DRD3 (0.42) | DRD2SLC6A4HTR2CDRD3GRM2 | |
| SCHEMBL2783024 | 0.81 | DRD2 (0.44) | DRD2DRD3GRM2 | |
| SCHEMBL5502949 | 0.80 | RBP4 (0.38) | DRD3UBE2MDCUN1D1GRM2 | |
| SCHEMBL2783825 | 0.80 | DRD2 (0.41) | DRD2HTR2CDRD3GRM2L3MBTL1 | |
| SCHEMBL2784006 | 0.80 | DRD2 (0.54) | DRD2SLC6A4HTR2CHTR7HTR2B | |
| SCHEMBL2785344 | 0.80 | DRD3 (0.43) | DRD2SLC6A4HTR2CDRD3GRM2 | |
| SCHEMBL2781688 | 0.79 | DRD2 (0.51) | DRD2SLC6A4DRD3GRM2 | |
| SCHEMBL2785313 | 0.79 | DRD2 (0.56) | DRD2SLC6A4DRD3GRM2 | |
| SCHEMBL2783328 | 0.78 | DRD2 (0.57) | DRD2SLC6A4DRD3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | claimed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |