Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 10/20 | 0.45 |
| ▸ | WNT3 | P56703 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503361 | 0.87 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL14997376 | 0.80 | DRD2 (0.46) | SFRP1WNT3DRD2ADRA1DADRA1A | |
| SCHEMBL4282334 | 0.80 | DRD2 (0.46) | SFRP1WNT3DRD2ADRA1DADRA1A | |
| SCHEMBL4281416 | 0.79 | STS (0.60) | SFRP1WNT3DRD2ADRA1DADRA1A | |
| SCHEMBL5502042 | 0.74 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL8269931 | 0.74 | EPHX2 (0.44) | SFRP1WNT3DRD2ADRA1DADRA1A | |
| SCHEMBL27683100 | 0.72 | HTR1A (0.52) | SFRP1DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL1498557 | 0.72 | TRPV4 (0.46) | HDAC8GAAHPGDRORCCACNA1B | |
| SCHEMBL13880104 | 0.71 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL8268664 | 0.71 | CACNA1B (0.53) | DRD2ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814851-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006040181-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2006-04-20 | — | — | WO | disclosed |