⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348727 | 0.91 | L3MBTL1 (0.46) | — | |
| SCHEMBL323980 | 0.85 | CA2 (0.53) | — | |
| Terephthalamide SCHEMBL7508927 | 0.82 | PARP1 (0.67) | — | |
| Benzamide SCHEMBL28225616 | 0.80 | PARP1 (0.73) | — | |
| SCHEMBL8727096 | 0.80 | ROCK1 (0.46) | — | |
| SCHEMBL9620387 | 0.79 | PARP10 (0.41) | — | |
| Terephthalamide SCHEMBL23774 | 0.78 | PARP1 (0.71) | — | |
| SCHEMBL28426696 | 0.78 | — | — | |
| SCHEMBL1535886 | 0.77 | ALDH1A1 (0.50) | — | |
| Terephthalamide SCHEMBL1087289 | 0.76 | PARP1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4897 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121013-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-13 | — | — | WO | claimed |
| US-20240116903-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2024-04-11 | — | — | US | claimed |
| CN-117732246-A | g-C 3 N 4 Preparation method and application of nano-sheet/KANF composite nanofiltration membrane | 浙江工业大学 | 2024-03-22 | — | — | CN | claimed |
| WO-2023249105-A1 | THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR DRUG-INDUCED MYOCARDIAL DISORDERS | 東レ株式会社 | 2023-12-28 | — | — | WO | claimed |
| WO-2023249107-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR PERIPHERAL NERVE DISORDER | 東レ株式会社 | 2023-12-28 | — | — | WO | claimed |
| WO-2023249106-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | 東レ株式会社 | 2023-12-28 | — | — | WO | claimed |
| WO-2023239846-A1 | HETEROCYCLIC COMPOUNDS AS PI3KΑ INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | claimed |
| US-20230357255-A1 | IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS | INCYTE CORPORATION | 2023-11-09 | — | — | US | claimed |
| EP-4269392-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | Toray Industries, Inc. (JP) | 2023-11-01 | — | — | EP | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| EP-0011048-B1 | A PROCESS FOR THE MANUFACTURE OF SUBSTANTIALLY PURE 3-AMINO-4-ALKOXY-ACYLANILIDES FROM 2,4-DINITROCHLOROBENZENE | Toms River Chemical Corporation (US) | 1982-01-27 | — | — | EP | claimed |
| US-4297357-A | ANTIULCER AGENTS; ANTISECRETORY AGENTS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-10-27 | — | — | US | claimed |
| US-4293306-A | Process for the dyeing and printing of hydrophobic synthetic organic fiber materials with water-insoluble azo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | claimed |
| US-4283556-A | Process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene | TOMS RIVER CHEMICAL CORPORATION (US) | 1981-08-11 | — | — | US | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-4247479-A | REACTING THE OXIME HYDROCHLORIDE WITH THREE MOLES OF ACETIC ANHYDRIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | claimed |
| US-4233445-A | SYNERGISTIC WITH SULFA DRUGS AS BACTERICIDES AND ANTIPROTOZOA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-11 | — | — | US | claimed |
| EP-0011048-A1 | A process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene | Toms River Chemical Corporation (US) | 1980-05-14 | — | — | EP | claimed |
| EP-0009608-A1 | N-Phenethylacetamide compounds, processes for their preparation and therapeutic compositions containing them | DAIICHI SEIYAKU CO., LTD. (JP) | 1980-04-16 | — | — | EP | claimed |
| US-4013768-A | VASODILATION, ANTIULCER, HYPOTENSIVE, DIURETIC, ANALGESIC, ANTIINFLAMMATORY | DELALANDE S.A. (FR) | 1977-03-22 | — | — | US | claimed |