Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958142 | 0.84 | THRB (0.46) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL1285930 | 0.81 | THRB (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL23111955 | 0.77 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL28995247 | 0.77 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| Ammonia Solution, Strong SCHEMBL4885946 | 0.76 | THRB (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL28404226 | 0.75 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| Carbamic Acid SCHEMBL30285522 | 0.73 | POLB (0.36) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13967508 | 0.73 | THRB (0.53) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL31425225 | 0.71 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL15019921 | 0.71 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789008-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GmbH (DE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006013111-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |