Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PON1 | P27169 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995247 | 0.99 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| Carbamic Acid SCHEMBL30285522 | 0.94 | POLB (0.36) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL1285930 | 0.89 | THRB (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL958142 | 0.84 | THRB (0.46) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL28398897 | 0.82 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL28404226 | 0.80 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL23111955 | 0.77 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL5504319 | 0.76 | THRB (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL8032848 | 0.75 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL31425225 | 0.73 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274074-A1 | Method for Controlled Free Radical Polymerization or Copolymerization of Methacrylic and/or Methacrylate Monomers or Exclusively Methacrylic and/or Methacrylate Copolymers | ARKEMA FRANCE (FR) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274074-A1 | Method for Controlled Free Radical Polymerization or Copolymerization of Methacrylic and/or Methacrylate Monomers or Exclusively Methacrylic and/or Methacrylate Copolymers | PRMT9, MMAB, PRMT8 | THRB 2111/4885POLB 2367/4885APEX1 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.