Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285930 | 0.89 | THRB (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL28995247 | 0.86 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL23111955 | 0.86 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| Ammonia Solution, Strong SCHEMBL4885946 | 0.84 | THRB (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL28404226 | 0.83 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| Carbamic Acid SCHEMBL30285522 | 0.81 | POLB (0.36) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13967508 | 0.81 | THRB (0.53) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL31425225 | 0.78 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL15019921 | 0.78 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| P-Xylene SCHEMBL11360520 | 0.77 | THRB (0.57) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4285888-A1 | COMPOSITE MATERIAL HAVING REDUCED POROSITY AND A PROCESS FOR PRODUCING THEREOF | DENTSPLY DETREY GmbH (DE) | 2023-12-06 | — | — | EP | claimed |
| US-6126922-A | DENTISTRY; ANHYDROUS MIXTURES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-03 | — | — | US | claimed |
| EP-0975306-A1 | DENTAL COMPOSITIONS WITH IMPROVED HANDLING CAPABILITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-02 | — | — | EP | claimed |
| WO-1998046197-A1 | DENTAL COMPOSITIONS WITH IMPROVED HANDLING CAPABILITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | claimed |
| US-12023392-B2 | Additive manufacturing process | DENTSPLY SIRONA INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240180791-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-20240164710-A1 | IMPLANT | SKULLE IMPLANTS OY (FI) | 2024-05-23 | — | — | US | disclosed |
| EP-3955881-B1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC (US) | 2024-04-24 | — | — | EP | disclosed |
| US-11931432-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11925697-B2 | Dental impression material | DENTSPLY SIRONA INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-11918664-B2 | Direct dental filling compositions | DENTSPLY SIRONA INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-11904030-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-02-20 | — | — | US | disclosed |
| WO-1999003444-A1 | DENTAL RESIN CEMENTS HAVING IMPROVED HANDLING PROPERTIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-28 | — | — | WO | disclosed |
| EP-0873107-A1 | FLUORIDE-RELEASING COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-28 | — | — | EP | disclosed |
| EP-0873106-A1 | USE OF METALLOFLUOROCOMPLEXES FOR DENTAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1998046198-A1 | DENTAL PRIMER COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046197-A1 | DENTAL COMPOSITIONS WITH IMPROVED HANDLING CAPABILITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1997018791-A1 | USE OF METALLOFLUOROCOMPLEXES FOR DENTAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-29 | — | — | WO | disclosed |
| WO-1997018792-A1 | FLUORIDE-RELEASING COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-29 | — | — | WO | disclosed |
| US-5063257-A | DENTAL GLASS IONOMER CEMENT COMPOSITIONS | G-C DENTAL INDUSTRIAL CORP. (JP) | 1991-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180791-A1 | DENTAL COMPOSITION | CAD, MTR, ESD | THRB 3466/4885POLB 246/4885APEX1 14/4885 |
| US-11925697-B2 | Dental impression material | FHIT, PASK, TAS2R40 | THRB 1625/4885POLB 1028/4885APEX1 2776/4885 |
| US-11904030-B2 | Dental composition | CBR3, CBR1, PRDX3 | THRB 4516/4885POLB 1605/4885APEX1 54/4885 |
| US-11931432-B2 | Dental composition | CAD, MTR, ESD | THRB 3466/4885POLB 246/4885APEX1 14/4885 |
| US-12023392-B2 | Additive manufacturing process | FLNA, FLNB, SAMM50 | THRB 1768/4885POLB 1371/4885APEX1 4338/4885 |
| US-11918664-B2 | Direct dental filling compositions | CAD, DOCK5, ITGA5 | THRB 4653/4885POLB 983/4885APEX1 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.