Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111621 | 0.86 | AR (0.61) | ARRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5114340 | 0.85 | AR (0.60) | ARRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5504376 | 0.82 | RAB9A (0.51) | ARRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5499298 | 0.79 | AR (0.63) | ARRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5534689 | 0.78 | AR (0.52) | ARRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5110226 | 0.77 | PTGDR2 (0.66) | KMT2AMEN1 | |
| SCHEMBL5500813 | 0.76 | AR (0.56) | ARRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5112506 | 0.74 | TDP1 (0.48) | RAB9ANPC1ALDH1A1LMNAKMT2A | |
| SCHEMBL5108644 | 0.74 | PTGDR2 (0.43) | RAB9AALDH1A1NPSR1MAPTHTT | |
| SCHEMBL5503332 | 0.73 | AR (0.63) | ARRAB9ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784182-A1 | 2-SULFANYL-BENZIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021418-A1 | 2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-02 | — | — | WO | disclosed |