Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 12/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569658 | 0.98 | HRH1 (0.40) | HRH1HRH3HRH2HRH4 | |
| SCHEMBL11005395 | 0.92 | — | — | |
| SCHEMBL7022926 | 0.89 | FAAH (0.38) | — | |
| SCHEMBL7029638 | 0.89 | FAAH (0.38) | — | |
| SCHEMBL7027055 | 0.89 | FAAH (0.38) | — | |
| SCHEMBL659550 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL14743990 | 0.81 | HRH1 (0.34) | HRH1HRH2 | |
| SCHEMBL9596022 | 0.80 | TLR7 (0.37) | — | |
| SCHEMBL14764836 | 0.80 | HDAC3 (0.34) | — | |
| SCHEMBL11510236 | 0.80 | FAAH (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758654-A1 | USE OF C-KIT INHIBITORS FOR TREATING PLASMODIUM RELATED DISEASES | AB Science (FR) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005102455-A1 | USE OF C-KIT INHIBITORS FOR TREATING PLASMODIUM RELATED DISEASES | AB SCIENCE (FR) | 2005-11-03 | — | — | WO | disclosed |