Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.83 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.74 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.74 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428095 | 0.89 | MEN1 (0.77) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL4432149 | 0.89 | RAB9A (0.84) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL5948558 | 0.88 | MEN1 (0.71) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL15323117 | 0.87 | MEN1 (0.69) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL4433023 | 0.86 | KCNK3 (0.84) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL6778380 | 0.84 | SGMS2 (0.76) | KCNK3KCNK9SGMS2RXFP1MAPK1 | |
| SCHEMBL7105901 | 0.84 | SGMS2 (0.70) | MEN1KMT2ARAB9ASGMS2MAPT | |
| SCHEMBL328592 | 0.83 | GAA (0.74) | MEN1KMT2ARAB9ARXFP1MAPT | |
| SCHEMBL5657294 | 0.83 | MEN1 (0.67) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL2116016 | 0.83 | RXFP1 (0.64) | MEN1KMT2ARAB9AKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | claimed |
| EP-3634372-A1 | COATED PARTICLES AND THEIR USES | Johnson & Johnson Consumer Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3541360-A1 | METHOD OF PROVIDING ORAL CARE BENEFITS | Fertin Pharma A/S (DK) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018213418-A1 | COATED PARTICLES AND THEIR USES | JOHNSON & JOHNSON CONSUMER INC. (US) | 2018-11-22 | — | — | WO | disclosed |
| WO-2018093501-A1 | METHOD OF PROVIDING ORAL CARE BENEFITS | FERTIN PHARMA A/S (DK) | 2018-05-24 | — | — | WO | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
| WO-1994026244-A1 | ORAL CARE COMPOSITIONS CONTAINING ZINC OXIDE PARTICLES AND SODIUM BICARBONATE | CHURCH & DWIGHT CO., INC. (US) | 1994-11-24 | — | — | WO | disclosed |