SCHEMBL5504816

SCHEMBL5504816

CC(C)N1CCC(N2[C]N(CCCN3CCC(F)(F)C3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.35
OPRM1 P35372 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5502126 0.77 SIGMAR1 (0.38)
SCHEMBL5504819 0.77 NSD2 (0.36) NSD2OPRM1
SCHEMBL5501529 0.73 HRH3 (0.32)
SCHEMBL5505552 0.71 HRH3 (0.48) OPRM1
SCHEMBL4382863 0.68 HRH3 (0.41) NSD2OPRM1
SCHEMBL5505365 0.68 HRH3 (0.34)
SCHEMBL5505360 0.68 HRH3 (0.34)
SCHEMBL5505485 0.68 CYP1A2 (0.38)
SCHEMBL23441910 0.65 HRH3 (0.40)
SCHEMBL23074854 0.64 GBA1 (0.37) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847530-A1 DIAMINE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-10-24 EP disclosed