Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504816 | 0.77 | NSD2 (0.35) | NSD2OPRM1 | |
| SCHEMBL5502129 | 0.75 | SIGMAR1 (0.41) | LMNAMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL5501533 | 0.74 | HRH3 (0.33) | LMNAHRH3 | |
| SCHEMBL23441910 | 0.74 | HRH3 (0.40) | L3MBTL1HRH3 | |
| SCHEMBL4382863 | 0.72 | HRH3 (0.41) | NSD2OPRM1HRH3 | |
| SCHEMBL22456361 | 0.70 | HRH3 (0.41) | L3MBTL1L3MBTL3HRH3 | |
| SCHEMBL25122519 | 0.69 | LMNA (0.39) | LMNAMEN1MAPTKMT2AMAOB | |
| SCHEMBL5505487 | 0.68 | CYP1A2 (0.45) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL5505363 | 0.68 | HRH3 (0.36) | HRH3 | |
| SCHEMBL5505366 | 0.68 | HRH3 (0.36) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |