Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504816 | 0.77 | NSD2 (0.35) | — | |
| SCHEMBL5501529 | 0.77 | HRH3 (0.32) | — | |
| SCHEMBL5502129 | 0.76 | SIGMAR1 (0.41) | SIGMAR1EBPKDM4EALDH1A1TSHR | |
| SCHEMBL5505365 | 0.71 | HRH3 (0.34) | — | |
| SCHEMBL5505360 | 0.71 | HRH3 (0.34) | — | |
| SCHEMBL5505485 | 0.68 | CYP1A2 (0.38) | ALDH1A1 | |
| SCHEMBL21871331 | 0.67 | ALDH1A1 (0.44) | KDM4EALDH1A1TDP1MEN1MAPT | |
| SCHEMBL10092701 | 0.67 | ALDH1A1 (0.44) | KDM4EALDH1A1TDP1MEN1MAPT | |
| SCHEMBL4386733 | 0.67 | HRH3 (0.42) | SIGMAR1EBPKDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11412105 | 0.65 | SIGMAR1 (0.67) | SIGMAR1EBPKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |