Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510391 | 0.88 | F10 (0.46) | WDR5NPY2RF10CNR2HTR1D | |
| SCHEMBL5506228 | 0.84 | NPY2R (0.41) | WDR5NPY2RF10CNR2ALOX15 | |
| SCHEMBL5511183 | 0.83 | NPC1 (0.41) | WDR5NPY2RF10CNR2CNR1 | |
| SCHEMBL5514263 | 0.81 | F10 (0.53) | NPY2RF10CNR2CNR1 | |
| SCHEMBL4467642 | 0.80 | F10 (0.54) | F10ALOX15HSD17B10NPC1RAB9A | |
| SCHEMBL4463968 | 0.75 | F10 (0.53) | F10ALOX15HSD17B10NPC1RAB9A | |
| SCHEMBL5568419 | 0.74 | NPY2R (0.42) | WDR5NPY2RF10CNR2CNR1 | |
| SCHEMBL5506905 | 0.74 | F10 (0.46) | WDR5NPY2RF10CNR2CNR1 | |
| SCHEMBL5505524 | 0.74 | F10 (0.40) | WDR5NPY2RF10 | |
| SCHEMBL5511036 | 0.73 | NPY2R (0.37) | WDR5NPY2RF10HRH3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |