Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479045 | 0.81 | AR (0.52) | F10MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5511183 | 0.76 | NPC1 (0.41) | NPY2RF10MAPTRAB9ANPC1 | |
| SCHEMBL5505029 | 0.73 | WDR5 (0.41) | NPY2RF10HRH3RAB9ANPC1 | |
| SCHEMBL5514263 | 0.72 | F10 (0.53) | NPY2RF10 | |
| SCHEMBL5568419 | 0.70 | NPY2R (0.42) | NPY2RF10MAPTRAB9ANPC1 | |
| SCHEMBL5565439 | 0.69 | F10 (0.59) | F10HRH3MAPTRAB9ANPC1 | |
| SCHEMBL5562241 | 0.69 | NPY2R (0.41) | NPY2RF10MAPTRAB9ANPC1 | |
| SCHEMBL5506905 | 0.67 | F10 (0.46) | NPY2RF10MAPTWDR5 | |
| SCHEMBL5510391 | 0.67 | F10 (0.46) | NPY2RF10WDR5 | |
| SCHEMBL849082 | 0.67 | ALDH1A1 (0.54) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |